Search on: GENERALIZED MYASTHENIA GRAVIS 
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Descriptor English:   Myasthenia Gravis 
Descriptor Spanish:   miastenia gravis 
Descriptor Portuguese:   Miastenia Gravis 
Synonyms English:   Generalized Myasthenia Gravis
Myasthenia Gravis, Generalized
Myasthenia Gravis, Ocular
Ocular Myasthenia Gravis  
Tree Number:   C10.114.656
C10.668.758.725
C20.111.258.500
Definition English:   A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459) 
Indexing Annotation English:   "myasthenia" unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congen consider MYASTHENIC SYNDROMES, CONGENITAL or specifics
See Related English:   Thymus Hyperplasia
 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DG diagnostic imaging DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RT radiotherapy
RH rehabilitation SU surgery
TH therapy UR urine
VE veterinary VI virology
Record Number:   9349 
Unique Identifier:   D009157 

Occurrence in VHL:
 

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